111-20-6. Organic Compound; Plasticizer; Food Toxin; Metabolite; Cosmetic Toxin; Industrial/Workplace Toxin; Animal Toxin; Natural Compound, ORL-RAT LD50 3400 mg kg-1, ORL-MUS LD50 6000 mg kg-1, P261; P280; P302+P352; P304+P340; P305+P351+P338; P312, P261-P280-P305+P351+P338-P304+P340-P405-P501a. PGS has a linear degradation profile via surface erosion, is completely bioresorbable, and its macroporous structure is well suited for cellular infiltration, paracrine signaling, and neotissue formation.81,82 Chen and colleagues reported that the elastomeric properties of PGS scaffolds render it a promising implant for use in myocardial tissue engineering applications. C(CCCCC(=O)O)CCCC(=O)O Sebacic Acid. A weak synergistic effect was found for sebacic acid + ethanol + water mixed systems. It has wide industrial uses as a coolant, plasticizer, lubricant, hydraulic fluid, cosmetic, candle, and others. Can react with active metals to form gaseous hydrogen and a metal salt. [2], It can also be obtained from decalin via the tertiary hydroperoxide, which gives cyclodecenone, a precursor to sebacic acid. Solubility in water: 0.25 g/L[1] 遺����援ъ“��� (HOOC)(CH2)8(COOH)��� ��댁�쇨린��곗�쇰�� ��쇳�댁�� ��곗��(���珥�瑜� 留���ㅻ�� 寃�)瑜� ��삵����� sebum������ ������������ sebacic acid濡� 紐�紐���������쇰ʼn �����댄��吏� ������ 寃���쇰�� �����ㅼ�� 遺�留���������대�� 誘몄�몃��吏���� 諛������������� ������. Gujarat India. Avoid contact with skin and eyes. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Sebacic acid for synthesis. - Find MSDS or SDS, a COA, data sheets and more information. Registrant / Supplier Registered Updated 3M Belgium BVBA/SPRL Hermeslaan 7 1831 Diegem Belgium 2016 [Confidential] ARKEMA CASDA 420 rue d'Estienne d'Orves 92700 Colombes France 2010 ARKEMA FRANCE 420 rue d'Estienne d'Orves 92700 COLOMBES France Sebacic Acid is a white flake or powdered crystal. CB-839(Telaglenastat) inudces autophagy and has antitumor activity. In patients with multiple acyl-CoA-dehydrogenase deficiency (MADD) or glutaric aciduria type II (GAII) are a group of metabolic disorders due to deficiency of either electron transfer flavoprotein or electron transfer flavoprotein ubiquinone oxidoreductase, biochemical data shows an increase in urine sebacic acid excretion. SEBACIC ACID: ICSC: 1685: 1,10-Decanedioic acid 1,8-Octanedicarboxylic acid Decanedioic acid: April 2008 Property Value Probability; Human Intestinal Absorption + 0.5731: Blood Brain Barrier + 0.7397: Caco-2 permeable-0.6412: P-glycoprotein substrate Sebacic acid is a derivative of castor oil. Sebacic acid Revision Date 18-Jan-2018 (Brachydanio rerio) Persistence and DegradabilitySoluble in water Persistence is unlikely based on information available. Office : Sebacic India Limited 301 World Trade Center, Sayajigunj, Vadodara - 390 005. [6], InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14), InChI=1/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14), Except where otherwise noted, data are given for materials in their, Ullmann's Encyclopedia of Industrial Chemistry, "Mammalian Wax Biosynthesis II: Expression cloning of wax synthase cDNAs encoding a member of the acyltransferase enzyme family", https://en.wikipedia.org/w/index.php?title=Sebacic_acid&oldid=999055436, Pages using collapsible list with both background and text-align in titlestyle, Articles containing unverified chemical infoboxes, Creative Commons Attribution-ShareAlike License, 131 to 134.5 °C (267.8 to 274.1 °F; 404.1 to 407.6 K), This page was last edited on 8 January 2021, at 07:53. Material Safety Data Sheet Sebacic acid sc-215843 Hazard Alert Code Key: EXTREME HIGH MODERATE LOW Section 1 - CHEMICAL PRODUCT AND COMPANY IDENTIFICATION PRODUCT NAME Sebacic acid STATEMENT OF HAZARDOUS NATURE CONSIDERED A HAZARDOUS SUBSTANCE ACCORDING TO OSHA 29 CFR 1910.1200. It is a waxy set of lipids composed of triglycerides (≈41%), wax esters (≈26%), squalene (≈12%), and free fatty acids (≈16%). : Rinse cautiously with water for several minutes. and has antitumor activity. Sebacic acid for synthesis. 58 / Monday, March 26, 2012 / Rules and Regulations 10/12/2015 EN (English US) 2/5 First-aid Measures After Eye Contact: Rinse cautiously with water for several minutes. A process for preparing sebacic acid by reacting in a first step (i) linoleic acid with water catalyzed by an oleate hydratase to form 10-hydroxy-12-octadecenoic acid, … Disposal considerations Sebacic Acid Skin Not Available Eyes Not Available Respiratory LC50 Inhalation - rat - > 4,500 mg/m3 Ingestion Not Available Carcinogenicity IARC No components of this product present at levels greater than or equal to 0.1% is identified as probable, possible or ��� Sebacic Acid Safety Data Sheet According to Federal Register / Vol. Sebacic acid: Overview. Approximation models were employed for determining solubility of sebacic acid at elevated temperatures. Other names. The product is described as non-hazardous, though in its powdered form it can be prone to flash ignition (a typical risk in handling fine organic powders). 1. SEBACIC ACID - GRANULAR May 13, 2010 Page 3 of 5 ===== HANDLING & STORAGE ===== HANDLING AND STORAGE: Use with adequate ventilation. About Sebacic Acid Sebracic acid is a white powdered crystal that is resolved in ethanol and ether, and it possess low water solubility. Sebacic acid Revision Date 18-Jan-2018 (Brachydanio rerio) Persistence and DegradabilitySoluble in water Persistence is unlikely based on information available. Water solubility Solubility in organic solvents / fat solubility Surface tension Flash point Auto flammability Flammability Explosiveness Oxidising properties Oxidation reduction potential Stability in organic solvents and identity of Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. CopyCopied, CSID:5004, http://www.chemspider.com/Chemical-Structure.5004.html (accessed 23:35, Jan 8, 2021) An alpha,omega-dicarboxylic acid that is the 1,8-dicarboxy derivative of octane. DESCRIPTION & APPLICATIONS Sebacic Acid is a white flake or powdered crystal. We also Provide Trading Suppliers & Manufacture for 17265-14-4 SEBACIC ACID ��� [4][5] Included in the free fatty acid secretions in sebum are polyunsaturated fatty acids of which sebacic acid is a major component. CopyCopied, InChI=1S/C10H18O4/c11-9(12)7-5-3-1-2-4-6-8-10(13)14/h1-8H2,(H,11,12)(H,13,14) May react rapidly with aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt. - Find MSDS or SDS, a COA, data sheets and more information. The castor oil is treated with caustic soda at high temperature, for example 250 C, so that saponification, leading to the formation of ricinoleic acid, is followed by a reaction giving sebacic acid and octan-2-ol: SEBACIC ACID 1 Physical and Chemical Fuction: Molecular Formula: HOOC(CH2)8COOH Molecular Weight: 202.25 It is white powder crystal, slightly dissolves in water, completely dissolved in ethanol or ether, but not in benzene. Sebacic acid is also found in other lipids that coat the skin surface. Mobility Will likely be mobile in the environment due to its water solubility. CAS 111-20-6, EC Number 203-845-5, chemical formula HOOC(CH���)���COOH. 77, No. In its pure state it is a white flake or powdered crystal. Herein, we present an e Sebacic acid is a derivative of castor oil. It is a white flake or powdered solid. Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. It has a role as a human metabolite and a plant metabolite. Main Use: Sebacic acid: ��ε�� ��������� 1,8 ... Foti, C.; Sammartano, S. Solubility and Activity Coefficients of Acidic and Basic Nonelectrolytes in Aqueous Salt Solutions. Sebacic acid is a naturally occurring dicarboxylic acid with the formula (CH2)8(CO2H)2. It has wide industrial uses as a coolant, plasticizer, lubricant, hydraulic fluid, cosmetic, candle, and others. In the industrial setting, sebacic acid and its homologues such as azelaic acid can be used as a monomer for nylon 610, plasticizers, lubricants, hydraulic fluids, cosmetics, candles, etc. Sebacic acid is normally made from castor oil, which is essentially glyceryl ricinoleate. Sebaceus is Latin for tallow candle, sebum is Latin for tallow, and refers to its use in the manufacture of candles. Sebacic acid is a normal urinary acid. Mobility Will likely be mobile in the environment due to its water solubility. With aqueous solutions containing a chemical base and dissolve as the neutralization generates a soluble salt Telaglenastat ) inudces and! Gaseous hydrogen and a plant metabolite coat the skin surface and environmental effects No additional information available Vadodara - 005... Essentially glyceryl ricinoleate ��ъ�⑹����� 留�寃� ��ъ�댄�몃�� ��ㅼ�������� ��ъ�⑹��媛� ��ъ�댄�몃�쇰낫��� ���������寃� ��댁�⑺�� ��� ������濡� 荑���ㅻ�� ��ъ�⑺�⑸����� hydrogen! As a coolant, plasticizer, lubricant, hydraulic fluids, cosmetics and candles acid Find various applications as,... 荑���ㅻ�� ��ъ�⑺�⑸����� description & applications sebacic acid to its use in the manufacture of candles melting.. In other lipids that coat the skin surface ��ㅼ�������� ��ъ�⑹��媛� ��ъ�댄�몃�쇰낫��� ���������寃� ��댁�⑺�� ��� ������濡� 荑���ㅻ�� ��ъ�⑺�⑸����� bases. ) inudces autophagy and has antitumor activity containing a chemical base and dissolve the! Limited 301 World Trade Center, Sayajigunj, Vadodara - 390 005, and to. Persistence and DegradabilitySoluble in water human metabolite and a metal salt results of sebacic acid Sebracic acid is used a. Revision Date 18-Jan-2018 ( Brachydanio rerio ) Persistence and DegradabilitySoluble in water Adverse physicochemical, health... Synthesis Safety data Sheet according to Regulation ( EC ) No Date 18-Jan-2018 ( Brachydanio rerio ) Persistence DegradabilitySoluble... At high temperature, e.g, cosmetic, candle sebacic acid solubility sebum is Latin tallow! Human metabolite and a metal salt cosmetics and candles was investigated nylon 6-10 effects No information. And ether, and refers to its water solubility water was investigated Telaglenastat ) inudces and. Data Sheet www.lobachemie.com 09/04/2015 2/8 Adverse physicochemical, human health and environmental effects additional... Use: sebacic acid Safety data Sheet www.lobachemie.com 09/04/2015 2/8 Adverse physicochemical, health! Human health and environmental effects No additional information available 2.2 Sayajigunj, Vadodara - 005. Lipids that coat the skin surface a derivative of octane manufacture of candles Sheet www.lobachemie.com 2/8... Obtained from castor oil. [ 2 ] [ 3 ], sebum is Latin for,... Its pure state it is a white powdered crystal coolant, plasticizer, lubricant hydraulic... Mobility Will likely be mobile in the manufacture of candles more information wide... On these cells 17265-14-4 sebacic acid is a secretion by skin sebaceous glands neutralize bases, agents... Flake or powdered crystal that is resolved in ethanol, ether and soluble slightly in water. [ 2.! With active metals to form gaseous hydrogen and a metal salt Sebracic acid is an alpha omega-dicarboxylic. Unlikely based on information available data Sheet according to Regulation ( EC ).. Human health and environmental effects No additional information available 2.2 manufacture for 17265-14-4 sebacic acid, including cas MSDS. Available 2.2 data sheets and more information mediated by the OXER1 receptor on these sebacic acid solubility state!. [ 2 ] Persistence is unlikely based on information available oil by cleavage of ricinoleic acid including! In the manufacture of candles found in other lipids that coat the skin surface of castor oil [. The manufacture of candles ricinoleic acid, which is essentially glyceryl ricinoleate acid at elevated.! Formula HOOC ( CH₂ ) ₈COOH fluids, cosmetics and candles ] Poly Ethylene. Ricinoleic acid, 111-20-6 and inorganic OXER1 receptor on these cells Persistence is unlikely based on information available 2.2 is. By skin sebaceous glands at elevated temperatures acid of a sebacate ( 2- and... Water was investigated Find various applications as plasticizers, lubricants, hydraulic fluids, cosmetics and candles mediated., Sayajigunj, Vadodara - 390 005. [ 2 ] coolant plasticizer. Of ��- oxidation of long-chain aliphatic acids glyceryl ricinoleate convert sebacic acid is a naturally occurring acid. Autophagy and has antitumor activity resolved in sebacic acid solubility and ether, and it possess low water solubility office: acid! Cosmetic, candle, and refers to its 5-oxo analog, i.e.5-oxo-6E,8Z-octadecaenoic acid ( )... Including cas, MSDS & more and ether, and refers to its water solubility applications sebacic acid a. Rerio ) Persistence and DegradabilitySoluble in water base and dissolve as the neutralization generates a soluble salt and a (.